Grand Bay National Wildlife Refuge has over 10,188 acres that sit on the beautiful Gulf Coast. The refuge is part of the Federal Gulf Coast National Wildlife Refuge Complex. The refuge sits along the Mississippi Sandhill Crane NWR and Bon Secour NWR on the MIssissippi border.

The refuge consists of tidal wetlands, salt marshes, Bayous, maritime forest, and wet pine savannas. The area also is home to several protected species including: the endangered brown pelican, threatened gopher tortoise and the endangered red-cockaded woodpecker.